Abstract

Bhupesh Yadav, Dr. Rajesh Mujariya, Dr. Manjeet Singh

ABSTRACT

This research focuses on the development and evaluation of fast-dissolving tablets of the anti-allergic drug Olopatadine. The tablets were formulated using a direct compression method with the incorporation of superdisintegrants for rapid disintegration. The excipients were sourced from reputable manufacturers and complied with safety standards. The pure drug (Olopatadine) was characterized, confirming its identity and quality. In-vitro dissolution studies demonstrated quick drug release, indicating the potential for rapid onset of action. Comparative studies of % drug release from different batches provided insights into formulation variations. The drug release kinetic study of the optimized batch revealed a diffusion-controlled release mechanism, best described by the Higuchi model. Future perspectives include formulation optimization, taste-masking techniques, in vivo studies, and regulatory approval for commercialization.