Abstract

Balram Rathore, Vivek Singh Thakur, B K Dubey, Deepak Kumar Basedia, Sunil Shah

ABSTRACT

Using a rat model of Freund's adjuvant-induced arthritis, this study sought to assess the anti-arthritis potential of Putranjiva roxburghii's hydroalcoholic extract by looking at how it affected paw volume, a crucial indicator of inflammation. In order to provide a thorough understanding of the extract's bioactive components and potential therapeutic effects, the research also evaluated the extraction yield, phytochemical profile, and chemical analysis of the extract. The hydroalcoholic extract's high yield was also noted in the study, indicating that it might be a useful source of bioactive substances. In light of the noteworthy anti-arthritic benefits seen in this animal model, Putranjiva roxburghii shows promise as a possible treatment for inflammatory conditions like arthritis. In order to assess the extract's safety and effectiveness in clinical trials, as well as to investigate the precise mechanisms by which it works, more research is required. The findings of this investigation add to the increasing amount of data demonstrating Putranjiva roxburghii’s therapeutic benefits and possible use in the management of long-term inflammatory diseases.