Abstract

Krishna Gupta, Pragya Sharma, Dr. Shailesh Jain, Dr. Rita Mourya

ABSTRACT

Medication adherence remains a critical challenge in chronic disease management, with significant implications for patient outcomes, healthcare utilization, and economic burden. This comprehensive review examines various strategies aimed at improving medication adherence in patients with chronic conditions. The review analyzes patient-related, healthcare provider-related, and system-level factors influencing adherence behaviors. Educational interventions, behavioral approaches, pharmaceutical interventions, technological innovations, and social support systems are evaluated for their effectiveness in enhancing adherence rates. The integration of digital health technologies, including mobile applications, electronic reminders, and telehealth services, has shown promising results, with studies demonstrating adherence improvements of up to 23% in certain populations. Simplified medication regimens and combination therapies have addressed treatment complexity barriers, while collaborative care models have successfully incorporated multidisciplinary approaches to chronic disease management. Despite these advances, significant implementation challenges persist, including technological barriers, patient and provider resistance, and concerns about program sustainability. This review identifies best practices for addressing these challenges and highlights opportunities for future research, particularly in developing personalized adherence interventions that account for psychosocial factors and diverse patient populations. The findings underscore the importance of individualized, multi-faceted approaches to medication adherence that recognize the complex interplay of factors affecting patient behavior in chronic disease management.