INVESTIGATION OF PHARMACOLOGICAL ACTIVITY OF ZN-ASPIRIN METAL COMPLEX BY USING STREPTOZOCIN INDUCED DIABETES ON RAT MODELS
Dimak Chand Sahu, Girendra Kumar Gautam, Durga Prasad Panda
ABSTRACT
Cataracts are quite prevalent when we get older. In fact, more than half of all Americans aged 80 or older either had cataracts or had surgery to get rid of cataracts. It may not have noticed at first that a person has a cataract. But over time, cataracts can make your vision blurred, blurred, or less colorful creating difficulties in day to day activities. Also, it is found that cataract is one of the main leading reason of blindness and visual impairment in diabetic patients. Patients with DM are identified to be up to 5 times more likely to develop cataracts, particularly at an early age. Due to the increasing prevalence of DM, the occurrence of diabetic cataracts has also increased. The present study aims to prepare and evaluate the effect of Zn-Aspirin Coordination Metal Complex on cataracts and its anti- diabetic activity by Streptozotocin (STZ) induced diabetes in Wistar rat model.
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